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People living with type 1 diabetes

Are you interested in research?

Would you like to find out about, or participate in, current projects? Find out about ongoing studies related to type 1 diabetes that you can participate in.

BETTER STUDIES

Find the studies related to the BETTER project. 

The IRCM clinic is searching for participants to participate in a research study that aims to prevent hypoglycemia in adults living with type 1 diabetes. 

This study involves 4 visits that can be undertaken over approximately 6 months:

  • A first visit to determine your eligibility to participate in the study. The duration of this visit is approximately 2 hours.
  • The other three visits (approximately 5 hours each) include a test carried out under medical supervision, during which we will lower your blood sugar by an insulin injection to test the effectiveness of an intake of 16g of carbohydrates to prevent or correct hypoglycemia at three different glycemic thresholds:
    • When blood sugar is less than 4.0 mmol/L
    • When blood sugar is equal to or less than 4.5 mmol/L
    • When blood sugar is 5.0 mmol / L or less

INCLUSION CRITERIA

  • Living with type 1 diabetes for more than one year
  • Be 18 years old and over 

INFORMATIONS

Virginie Messier 514 987-5696 or by email virginie.messier@ircm.qc.ca 

Dr. Claudia Gagnon’s research laboratory, located at the Centre de recherche du CHU de Québec (CHUL site) – Université Laval, is looking for parents or guardians of children living with type 1 diabetes to participate in a research project. This is a simulation study of administration of intranasal glucagon compared to injectable glucagon after viewing short videos. You will then be invited to give your comments during an interview.

A financial compensation will be offered.

Involvement

Participation consists of viewing three videos (approximately 6 minutes in total) and a single visit to Université Laval to participate in the simulated administration of injectable and intranasal glucagon as well as a short one-on-one interview.

Inclusion criteria

  • Parent or guardian of a child (<18 years old) living with type 1 diabetes
  • No repeated experiences in the administration of glucagon

Information

If you are interested, contact the person responsible for the project at 418-525-4444 extension 48729 or write to the following email address: yue-pei.wang.1@ulaval.ca.

 

OTHER STUDIES

The IRCM clinic is looking for participants to participate in a research project aiming to restore hypoglycemia awareness with home-based high intensity interval training in adults with type 1 diabetes and impaired awareness of hypoglycemia.

INVOLVEMENT

This study involves 2 visits in personne or by phone and 18 visits by phone that can be undertaken over a period of about 16 weeks:

  • A pre-inclusion visit by telephone to answer to a question about your perception of hypoglycemia symptoms. If we confirm that you have an impaired awareness of hypoglycemia, you can proceed to the next step of this study.
  • A first visit takes place either at the IRCM or by telephone/videoconference to determine your eligibility. This visit lasts approximately 1.5 hours.
  • A 4-week run-in period that aims to optimize your diabetes treatment. During this period, 30-minute telephone/videoconferencing visits will take place every week.
  • You will be randomly assigned to one of the following two groups for the 12-week intervention period:
    • Group 1: Standard educational program to prevent hypoglycemia. This program includes 2 sessions of 45 minutes each.
    • Group 2: Standard educational program to prevent hypoglycemia combined with a high-intensity interval training program. The educational program includes 2 sessions of 45 minutes each. The training program will be carried out at your home 3 times a week.

During the intervention period, telephone/videoconference visits will take place every week for the first 4 weeks and then every 2 weeks thereafter. These visits last about 30 minutes each.

  • An end-of-study visit takes place either at the IRCM or by telephone/videoconference in order to assess your perception of hypoglycemia symptoms. This visit lasts 45 minutes.

During the study period, you will continue to use your own continuous glucose monitoring system.

Expected benefits: you will benefit from the advices of a healthcare professional trained in diabetes and have access to a free training program if you are in group 2.

Financial compensation will be given for the first and last visit.

INCLUSION CRITERIA

  • Have type 1 diabetes for at least 5 years
  • Be between 18 and 65 years old
  • Use a continuous glucose monitor (or Flash glucose monitor)
  • Have impaired awareness of hypoglycemia (will be evaluated with 1 question)

INFORMATIONS

The McGill University Health Centre, The Hospital for Sick Children, University Health Network (UHN) and other pediatric and adult care centers in Ontario and Quebec are conducting a study to better understand the perceived gaps and opportunities in care for patients living with type 1 diabetes (T1D) transitioning from pediatric to adult care.

The transition period from pediatric to adult care is difficult for people who live with T1D. In Ontario and Quebec, people often get “lost” in the health care system, resulting in low clinic attendance, difficult management of blood glucose levels and the development of complications requiring emergency care.

Feedback from the first phase of this study will help design a text message algorithm that could help “keep in touch” with transitioning youth, collect important analytics during this time, and better guide clinical care.

INVOLVEMENT

This study involves participating in an activity, either a semi-structured interview (individual) or a co-design workshop (individual or group). You will need 1-2 hours to complete the study, which will be conducted by phone or teleconference (using Microsoft Teams). You will receive a $50 Amazon gift card in recognition of your contribution.

INCLUSION CRITERIA

  • Living with type 1 diabetes
  • Be between 16 and 25 years of age
  • Reside in Ontario or Quebec

INFORMATION

  • Madison Taylor, UHN study coordinator, at 437-996-8998 or by email at madison.taylor2@uhn.ca

The Clinic of the Institut de recherche cliniques de Montréal (IRCM) is seeking participants for a research project on the effectiveness of basal insulin dose reduction in reducing hypoglycemia during continuous exercise and interval exercise in adolescents and adults with type 1 diabetes using the insulin pump. The objective of this study is to test strategies to reduce the risk of hypoglycemia during and after exercise.

Financial compensation will be given. The project is being carried out under the supervision of Dr. Laurent Legault (Montreal Children’s Hospital), Dr. Rémi Rabasa-Lhoret (IRCM) and Dr. Melanie Henderson (Centre hospitalier universitaire Sainte-Justine).

INVOLVEMENT

This study involves five visits (Montreal) within a period of five months. The first 3-hour visit aims to determine your eligibility. Subsequently, four visits are planned to test two different strategies to reduce hypoglycemia during exercise (continuous or interval): reducing the basal insulin dose by 80% 90 minutes before the start of exercise, and reducing the basal insulin dose by 40% 90 minutes before the start of exercise.

Both strategies will involve two 3.5-hour visits to the IRCM. The effectiveness of two post-exercise strategies to reduce the risk of post-exercise hypoglycemia will be evaluated by reducing the basal insulin dose and reducing the dinner bolus, and snacking after exercise, regular bolus at dinner and afternoon snack.

INCLUSION CRITERIA

  • Have been diagnosed with type 1 diabetes for more than two years
  • Be over 14 years of age
  • Use the insulin pump for at least 3 months

INFORMATIONS

The IRCM clinic is searching for participants to participate in a research study that aims to compare commercially available automated insulin delivery (AID) systems and do-it-yourself (developed by patients) AID systems in terms of glucose control, safety and quality of life in real-life conditions in adults living with type 1 diabetes. 
Participants have the possibility to gain knowledge that will enable them to better their current treatment. 

This study involves 5 visits that can be undertaken over approximately 12 weeks:

  • A first visit to determine your eligibility to participate in the study will take place either at the research center or by telephone/video conference. The duration of this visit is approximately 1.5 hours.
  • If your first visit is at the IRCM, you will do visit 2 right after visit 1. If your first visit is online, you will be asked to schedule a date and time for visit 2 so that the study material can be sent to you. The duration of visit 2 is approximately 60 minutes.
  • Three telephone visits to collect information on glucose control, safety, quality of life and insulin delivery. The duration of visit 3, 4 and 5 are approximately 40, 30 and 30 minutes, respectively.

INCLUSION CRITERIA

  • Living with type 1 diabetes for more than one year
  • Be 18 years old and over 
  • Using an automated insulin delivery (AID) system for more than 3 months

INFORMATIONS

Anne Bonhoure
514 914 1585
Anne.bonhoure@ircm.qc.ca 

Dr. Stephanie Chevalier’s team at McGill University is recruiting participants living with type 1 and type 2 diabetes to take part in a study evaluating the role of technology in dietary monitoring.

INVOLVEMENT

This study involves monitoring your diet for 8 days.  For 4 days, you will use a mobile application. For the next 4 days, you will use an online dietary recall tool. The order of the interventions may vary.

The study also involves sending recent measurements of your weight and height.

INCLUSION CRITERIA

  • Living with or without diabete
  • Be between 18 and 70 years of age
  • Own a smartphone or tablet
  • Not on a weight loss diet

INFORMATIONS

Aviva Rappaport or Dr. Stéphanie Chevalier by email at Chevalierlabo@gmail.com

The IRCM clinic is seeking volunteers for a research project on the comparison of ultra-fast acting insulin (FIASP) and fast acting insulin (Novorapid) on blood sugar management during exercise following a meal. 

Financial compensation will be given. The project is being carried out under the supervision of Dr. Rémi Rabasa-Lhoret.

INCLUSION CRITERIA

  • Clinical diagnosis of type 1 diabetes for at least 1 year
  • Be over 18 years of age
  • Using multiple daily injections as a treatment modality (basal/bolus)

INVOLVEMENT

This study involves a total of five visits (Montreal), including one admission visit and four intervention visits. The admission visit lasts about two hours and will determine your eligibility to participate in the study. 

Intervention visits last about five hours. Breakfast will be served in the morning and two different strategies will be tested: one-hour cycling one hour after the meal, and two hours after the meal.

INFORMATIONS

 
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