Ongoing studies

T-Hypo study


The current recommendation for the treatment of hypoglycemia is to consume 15 to 20g of carbohydrates, wait 15 minutes before measuring the blood sugar and repeat the treatment if hypoglycemia persists. However, this recommendation is based on studies conducted some 30 years ago and with different insulins from the insulin analogues currently used. In addition, it has been reported that a large majority of patients consume more than 20g of carbohydrates to treat hypoglycemia. Recent data also suggests that a treatment with 15g of carbohydrates does not treat a significant proportion of hypoglycemia. The objective of this study is to determine whether the current recommendation for the treatment of hypoglycemia should be updated.

To participate in this study, you must: 1) be over 18 years of age; 2) have had type 1 diabetes for more than one year; 3) use the insulin pump or multiple insulin injections.

You will have to come to the IRCM 5 times. The first visit (3 hours) aims to confirm your eligibility. The other four visits are aimed at testing two treatments to correct induced hypoglycemia at two different glycemic thresholds:

  • A 16g carbohydrate treatment when blood glucose is below 3.0 mmol / L
  • A 32g carbohydrate treatment when blood glucose is below 3.0 mmol / L
  • A 16g carbohydrate treatment when the blood glucose is between 3.0 and 3.5 mmol / L
  • A 32g carbohydrate treatment when the blood glucose is between 3.0 and 3.5 mmol / L

Financial compensation will be given for each completed visit.

To learn more about this study, contact: Valérie Parent, nurse: 514-987-5581 or valerie.parent@ircm.qc.ca